Determination of di(2-ethylhexyl) phthalate in plastic medical devices

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Extraction, localization, and metabolism of di-2-ethylhexyl phthalate from PVC plastic medical devices.

The results of our studies on the extraction and disposition of three plasticizing substances which are extracted from poly(vinyl chloride) medical devices will be reported. The plasticizers are di-2-ethylhexyl phthalate (DEHP), di-2-ethylhexyl adipate (DEHA), and butylglycolyl butyl phthalate (BGBP). DEHP extraction will be described in greater detail, and the two other plasticizers, DEHA and ...

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Evaluation of the Di(2-ethylhexyl)phthalate released from polyvinyl chloride medical devices that contact blood

Extraction methods that simulate those used in the clinic are recommended for obtaining extraction solutions. For polyvinyl chloride (PVC) medical devices that have contact with human blood, an alternative medium (ethanol/water mixture) is suggested as an extraction screening vehicle to evaluate the di(2-ethylhexyl)phthalate (DEHP) released. A test comparing the extraction ability between the a...

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Di2-ethylhexyl phthalate disrupts thyroid hormone homeostasis through activating the Ras/Akt/TRHr pathway and inducing hepatic enzymes

Di(2-ethylhexyl) phthalate (DEHP), as a widespread environmental pollutant and an endocrine disruptor, can disturb the homeostasis of thyroid hormones (THs). In order to elucidate roles of the MAPK and PI3K/Akt pathways and hepatic enzymes in thyroid-disrupting effects of DEHP, Sprague-Dawley rats were dosed with DEHP by gavage for 30 consecutive days; Nthy-ori 3-1 cells were treated with DEHP ...

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Validation and application of an HPLC method for determination of di (2-ethylhexyl) phthalate and mono (2-ethylhexyl) phthalate in liver samples.

A reversed-phase gradient elution, UV detection method is developed for the simultaneous determination of mono (2-ethylhexyl) phthalate [MEHP] and di (2-ethylhexyl) phthalate [DEHP] in tissue samples. The method is validated with respect to extraction recovery, inter and intra-day precision, linearity of response, detect ability, and specificity. The validated method has been successfully appli...

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The adsorption of Bis (2-ethylhexyl) phthalate (DEHP) on the carbon adsorbents (Chezacarb S and Chezacarb SH) and polymer adsorbent on basis of polypropylene with polyethylene (Reo Fb) was studied. Efficiency of DEHP adsorption (concentration DEHP to 10 g.L, concentration of the adsorbents 1.7 g.L) was more then 99.9 %. By the sample from groundwater was efficiency more as 99.7 % in the case of...

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ژورنال

عنوان ژورنال: Hemijska industrija

سال: 2016

ISSN: 0367-598X,2217-7426

DOI: 10.2298/hemind141129023k